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Thursday, March 25, 2010

Getting Started in Gene Orthology and Functional Analysis


The latest innovations and rapid progress in sequencing technologies have substantially enriched whole genome data. Each genome consists of a unique gene inventory, which determines the specific phenotype and interaction with the environment. After 3.5 billion years of evolution, the number of species has expanded considerably. These species originated from simple life forms and have been confronted with complicated environmental changes. These variations, as a result of natural selection, are encoded in their genomes and provide clues to their genetic divergence from a common ancestor. The inference of variations between species by analyzing compositions of gene inventories therefore opens the door to the rich branch of comparative genomics.

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